Royal Society of Chemistry

Materials Horizons J Mat Chem B Materials Advances Biomaterials Science Nanoscale

Ivyspring International Publisher

Theranostics

Elsevier

Acta Biomaterialia

mdpi

Pharmaceutics Gels

Taylor and Francis

Science and Technology of Advanced Materials

Program

The Special Event

40th Anniversary Symposium of The Japan Society of Drug Delivery System

Reflecting on the Past and Considering the Future of the Japan DDS Society

Chair
Yasuhiko Tabata
(Kyoto University)

Special Lecture I

July 10 (Wednesday) 9:00-9:45, Venue A (1st Floor Grand Hall)

From Pharmacokinetics to Controlled Intracellular Trafficking to University Originated Nanomedicines (Tentative)

Chair
Yukio Nagasaki
(University of Tsukuba)
Speaker
Hideyoshi Harashima
(Hokkaido University, Distinguished Professor)
Hideyoshi Harashima

Special Lecture II

July 10 (Wednesday)13:30-14:15 Venue A (1st Floor Grand Hall)

Gut Frailty: Its Concept and Pathogenesis

Chair
Yukio Nagasaki
(University of Tsukuba)
Speaker
Yuji Naito
(Kyoto Prefectural University Professor)
Yuji Naito

Special Lecture III

July 11 (Thursday) 9:00-9:45, Venue A (1st Floor Grand Hall)

Extrahepatic delivery of siRNA, a theranostic approach

Chair
Akihiko Kikuchi
Speaker
Ick Chan Kwon
(KIST, Principal Research Scientist)
Ick Chan Kwon

Chairperson's Address

July 9 (Tueseday) 17:00-17:45,

Towards a New Stage of Challenges

Chair
Yasuhiko Tabata
(Kyoto University)
Speaker
Yukio Nagasaki
(University of Tsukuba)

English Session Invited Lectures

Featured speaker 1

Multicompartment Polyion Complex Micelles based on Triblock-Copolypept(o)ides with tailored Functionality in Cancer Therapy

Chair
Koichi Shiraishi
The Jikei University School of Medicine
Speaker
Matthias Barz
Leiden Academic Center for Drug Research (LACDR)
Matthias Barz

Featured speaker 2

“Modulation of Nitric Oxide for the treatment of inflammatory disease"

Chair
Yuta Koda
(University of Tsukuba)
Speaker
Won Jong Kim
Department of Chemistry School of Interdisciplinary Bioscience and Bioengineering  Pohang University of Science and Technology (POSTECH)
Won Jong Kim

Featured speaker 3

Designing Polymer Assemblies for Therapeutic Nanoreactors and for Evading Macrophage Uptake

Chair
Youn Soo Kim
（POSTEC）
Speaker
Tomoki Nishimura
Department of Chemistry and Materials, Faculty of Textile Sciences, Shinshu University
Tomoki Nishimura

Featured speaker 4

Development of plant-derived nanoparticles as a new class of DDS

Chair
Akon Higuchi
(Wenzhou Medical University, National Central University)
Speaker
Shoko Itakura
Laboratory of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science
Shoko Itakura

Featured speaker 5

Advances in Biomaterial Design for Ocular Pharmacotherapy

Chair
Shoko Itakura
Laboratory of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science
Speaker
Jui-Yang Lai
(Chang Gung University)
Jui-Yang Lai

Featured speaker 6

Cancer Theranostics

Chair
Tomoki Nishimura
(Department of Chemistry and Materials, Faculty of Textile Sciences, Shinshu University)
Speaker
Xiaoyuan Chen
(National University of Singapore)
Xiaoyuan Chen

Featured speaker 7

Magnetic temperature responded thin film actuator for drug releasing control

Speaker
Tzong-Rong Ger
Chung Yuan Christian University
Tzong-Rong Ger

Symposiums

Symposium 1

The Evolution of Nucleic Acid Medicine and DDS: Toward the Next Generation of Nucleic Acid Therapeutics

Symposium
Chair
Kanjiro Miyata
(The University of Tokyo)
Shigeki Sasaki
(Nagasaki International University)
Speaker
Shigeki Sasaki
(Nagasaki International University)
Development and outlook for nucleic acid therapeutics
Speaker
Hiroshi Abe
(Nagoya University)
Development of mRNA medicine based on chemistry.
Speaker
Norihumi Shioda
(Kmamoto University)
Targeting nucleic acid structures to develop therapeutics for neurological diseases
Speaker
Takanori Kanazawa
(Tokushima University)
Nucleic acid delivery to deeper regions of central nervous system by nose-to-brain nano-DDS
Speaker
Makiya Nishikawa
(Tokyo University of Science)
Delivering oligonucleotide therapeutics through the control of their interaction with biocomponents
Speaker
Kanjiro Miyata
(The University of Tokyo)
Challenges of polymeric nanomedicines for overcoming the biological barriers

Symposium 2

DDS and immunity: Challenges for drug and vaccine development

Symposium
Chair
Keiji Itaka
(Tokyo Medical and Dental University・Osaka University)
Yasuo Yoshioka(OSAKA UNIVERSITY)
Speaker
Tsutomu Suzuki
(Department of Chemistry and Biotechnology, University of Tokyo)
Chemistry of modified nucleic acids
Speaker
Hironori Nakagami
(Osaka University School of Medicine, Health and Developmental Medicine)
Peptide vaccine
Speaker
Rikinari Kayama
(Kanazawa University, Faculty of Medicine, Immunology)
Artificial exosomes
Speaker
Yasuo Yoshioka
(Osaka University Biken)
Vaccines/Immunology
Speaker
Keiji Itaka
(Tokyo Medical and Dental University/Osaka University)
mRNA vaccines/mRNA drug discovery

Symposium 3

Ex Vivo 3D Tissue Formation Techniques for DDS Research

Symposium
Chair
Yoshikatsu Koga
(National Cancer Center)
Mitsunobu Kano
(Okayama University)
Speaker
Satoshi Konishi
（Kyoto University）
Speaker
Yuzuru Ito
（University of Tsukuba）
Speaker
Ryo Tsumura
（National Cancer Center）
An evaluation of antibody therapeutics using patient-derived cancer organoids
Speaker
Nobuhito Mori
（AIST）
Novel perfusable organoid models toward DDS research

Symposium 4

Paradigm Shift from Biocompatibility to Materials Symbiosis

Symposium
Chair
Mitsuhiro Ebara
(National Institute for Materials Science)
Takeshi Mori
(Kyushu University)
Speaker
Asako Yamayoshi
(Nagasaki University)
Development of exosome-hijacking DDS enabling material symbiosis of artificial nucleic acids
Speaker
Daisuke Takahashi
(Keio University)
Establishment of gut bacteria-host symbiosis and its application to material symbiosis
Speaker
Minako Ito
(Kyushu University)
Strategies to control inflammation in the brain
Speaker
Yasuhide Nakayama
(Biotube)
In-body tissue architecture technology can produce symbiotic biomaterials through foreign body reaction
Speaker
Toida Tsutomu
(AIST)
Reduction of foreign body reactions to implantable medical devices by phosphatidylserine coating

Symposium 5

New Developments in DDS Research Based on Pharmaceutical Science & Technology

Symposium
Chair
Takanori Kanazawa
(Tokushima University)
Noriyasu Kamei
(Kobe Gakuin University)
Speaker
Noriyasu Kamei
(Kobe-Gakuin University)
Drug targeting to hippocampal neurons via engineering functional fusion proteins
Speaker
Hiroki Tanaka
(Tohoku University)
Recent findings regarding freezing, lyophilization, etc. of LNP preparations
Speaker
Mika Yoshimura Fujii
(Shiseido Co., Ltd., MIRAI Tachnology Institute)
Development of Technology for Delivering High Molecular Weight Hyaluronan into Stratum Corneum and Its Application to Cosmetic Formulations
Speaker
Hiromu Kondo
(University of Shizuoka)
Novel value creation of oral DDS formulation using nano fiber technology
Speaker
Tatsuhiro Ishida
(Tokushima University)
Ionic liquid as an adsorption enhancer for peptides and siRNA

Symposium 6

Reactive Oxygen, Nitrogen, Sulfur Species, and Redox-Related Molecules

Symposium
Chair
Jun Fang
(Sojo University)
Urara Hasegawa
(Pennsylvania State University)
Speaker
Takaaki Akaike
(Tohoku University)
Supersulfide biology and translational medicine for disease control
Speaker
Yu Ijima
(Kyoto Pharmaceturila University)
Development of delivery systems for nitric oxide and supersulfides using endogenous proteins
Speaker
Takuto Toriumi
(Shimane University)
Enhancement of exercise performance by tissue specific reactive oxygen species regulation
Speaker
Urara Hasegawa
(Penn State)
Polymeric micelles for therapeutic delivery of hydrogen sulfide and polysulfide species
Speaker
Jun Fang
(Sojo University)
Polymeric micelle encapsulating carbon monoxide as a nanomedicine for inflammatory diseases and cancer

Workshops

Workshop 1

Conquering the Barriers of Solid Tumor Microenvironment in DDS

Workshop
Chair
Kensuke Osada
(National Institutes for Quantum Science and Technology)
Hiroto Hatakeyama
(Chiba University)
Hiroki Takashima
(National Cancer Center)
Speaker
Yasuyuki KIDA
(AIST)
Challenges of DDS in Pancreatic Cancer Treatment: Development of a Pancreatic Cancer Microenvironment Experimental Model Focusing on CAF
Speaker
Yoshiyuki YAMAMOTO
(University of Tsukuba)
An Overview of Irinotecan Liposome, ONIVYDE®: Antitumor Mechanism, Clinical Development and Future Prospects
Speaker
Horacio CABRAL
(The University of Tokyo)
Speaker
Hiroyasu TANAKA
(Okayama University)
Speaker
Hidefumi MUKAI
(Nagasaki University)
Speaker
Hiroto HATAKEYAMA
(Chiba University)

Workshop 2

DDS through Fusion of Drugs and Devices - Cutting-edge Research in Academia and Industry -

Workshop
Chair
Kentaro Kogure
(Tokushima University)
Hiroaki Kasukawa
(Terumo Corporation)
Speaker
Ryo Suzuki
Development of new strategies for cancer treatment using ultrasound
Speaker
Kentaro Kogure
Development of a new DDS using electricity
Speaker
Akira Matsumoto
To improve the quality and unconsciousness of medication management at home -
Speaker
Syunsuke Yamamoto
Direct Drug Delivery to the Brain via Intranasal Administration: Challenges and Prospects for Societal Implementation

Workshop 3

Challenges in the Creation of Next Generation DDS - From the Perspective of Intestinal Environment and Energy Metabolism

Workshop
Chair
Yutaka Ikeda
(University of Tsukuba)
Yuma Yamada
(Hokkaido University)
Speaker
Yutaka Ikeda
(University of Tsukuba)
Speaker
Yuma Yamada
(Hokkaido University)
Speaker
Inoue Ryo
(Setsunan University)
Speaker
Shiiba Isshin
(Gakushuin University)

Workshop 4

Harmonization and Regulation for the Development of New Modality Products

Workshop
Chair
Kohsaku Kawakami
(National Institutes for Materials Science)
Akiko Ishii
(National Institute of Health Sciences)

Education Session

Coordinator
Masamichi Nakayama
(Tokyo Women's Medical University)
Mitsuhiro Ebara
(NIMS)

Part 1

13:00-15:15 (in no particular order)

Speaker
Nobuhiro Nishiyama
(Tokyo Institute of Technology)
Study on nanoDDS based on precision design of synthetic polymers
Speaker
Yoshiki Katayama
(Kyushu University)
The immune system and DDS that utilizes it
Speaker
Hiroto Hatakeyama
(Chiba University)
Re-thinking of delivery strategy of antibodies and DDSs to tumors

Part 2

15:30-17:30 (in no particular order)

Speaker
Yuma Yamada
(Hokkaido University)
The ABCs of Lipid nano particle preparation
Speaker
Hiroki Takashima
(National Cancer Center)
Selection of tumor models in drug delivery system development
Speaker
Mitsuhiro Ebara
(NIMS)
How to use color effectively in your presentations
Speaker
Masamichi Nakayama
(Tokyo Women's Medical University)
Living radical polymerization for DDS research

Corporate Presentations

Cutting-edge technology for DDS from exhibiting companies

Coordinators
Akihiko Kikuchi
(Tokyo University of Science)
Yoshitsugu Akiyama
(Tokyo University of Science)

English Session（Onsite⁻Online Hybrid）

Yuta Koda
(University of Tsukuba)
Youn Soo Kim
(POSTEC)
Kanjiro Miyata
(The University of Tokyo)
Akon Higuchi
(Wenzhou Medical University, National Central University)
Koichi Shiraishi
(The Jikei University School of Medicine)
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